The ME jumper allows the manual (Ex. FPT tool…) access (read/write operations) to the SPI regions of the FD… not primary related to AMI tools like AFU…
A bios_region only dump (dumps made with FPT) can be made and work only in this region, then merged back in to main image.
You should focus on updating only mcodes and see how it goes, then work the variables to unlock and further trials… rushing and messing too much things at the time will lead you to a “death” motherboard.
Nothing more to add, good luck.