RX580 no video, BIOS options greyed out

Hey all. I have an Acer Veriton M4650G that I use as my living room emulator PC and I’m trying to upgrade the integrated graphics to a RX580 I had kicking around. When I install the RX580 I get one short beep indicating the PC has posted but I get nothing from the HDMI port, and nothing from the Integrating GPU HDMI port either. If I uninstall the RX580 everything goes back to working normally through the Integrated GPU. I know the RX580 works fine as I tested it in another PC. The video output is set to integrated in my BIOS and I can’t change it (the option is greyed out and unselectable) I have updated my BIOS to the latest version available, replaced the CMOS battery and every other little thing I can think of to no avail. Please help!